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AutoSubSync is a user-friendly Python tool that automatically synchronizes your subtitles with your videos using powerful tools such as ffsubsync and alass. It also lets you manually adjust the subtitle timings. Just drag and drop your files, and let AutoSubSync do the rest, making subtitle alignment both simple and efficient.
Developer Friendly Kubernetes 
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Cyclops is an open-source dev tool that simplifies Kubernetes with an easy-to-use UI, making it less intimidating. Instead of creating and configuring your Kubernetes manifests with YAML, use Cyclops to painlessly configure and deploy your applications - validations included!
Python GUIs for Humans! PySimpleGUI is the top-rated Python application development environment. Launched in 2018 and actively developed, maintained, and supported in 2024. Transforms tkinter, Qt, WxPython, and Remi into a simple, intuitive, and fun experience for both hobbyists and expert users.
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A GUI for controlling Gatekeeper, unquarantining apps and more.
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GUI for immich-go.
Immich-Go GUI is a graphical front-end for immich-go, a tool for managing media uploads to the Immich server. This GUI simplifies the process of configuring, launching, and monitoring immich-go.
Visual tool to explore SQLite databases page-by-page, the way they're stored on disk and the way SQLite sees them.
A small GUI application built in redbean that lets you explore your SQLite databases "page by page" the way SQLite sees them.
Turn (almost) any Python command line program into a full GUI application with one line.
Gooey converts your Console Applications into end-user-friendly GUI applications. It lets you focus on building robust, configurable programs in a familiar way, all without having to worry about how it will be presented to and interacted with by your average user.
CoolerControl is a feature-rich cooling device control application for Linux. It has a system daemon for background device management, as well as a GUI to expertly customize your settings.
CoolerControl depends on Hwmon kernel drivers and liquidctl to access and control supported hardware.
An unofficial GUI wrapper around the Tailscale CLI client.
Trayscale is an unofficial GUI interface for the Tailscale daemon particularly for use on Linux, as no official Linux GUI client exists. It provides a basic system tray icon and a fairly comprehensive UI with support for many of Tailscale's features.
Conky is a free, light-weight system monitor for X, that displays any kind of information on your desktop. It can also run on Wayland (with caveats), macOS, output to your console, a file, or even HTTP (oh my!).
An immediate mode GUI written in Rust.
egui is an immediate mode GUI library written in Rust. egui runs both on the web and natively on 
. On the web it is compiled to WebAssembly and rendered with WebGL. Everything you see is rendered as textured triangles. There is no DOM, HTML, JS or CSS. Just Rust.
Create, edit, browse SQLite databases.
Btrfs Assistant is a GUI management tool to make managing a Btrfs filesystem easier.
Manage Kubernetes in style.
JET Pilot is an open-source Kubernetes desktop client that focuses on less clutter, speed and good looks.
Meet the NiceGUI. And let any browser be the frontend of your Python code.
Create web-based user interfaces with Python. The nice way.
NiceGUI is an easy-to-use, Python-based UI framework, which shows up in your web browser. You can create buttons, dialogs, Markdown, 3D scenes, plots and much more.
An elegant virtual machine manager for the desktop.
Quickgui is a graphical user interface for the Quickemu virtual machine manager. Quickgui enables you to create and manage virtual machines from a simple and elegant interface. Nearly 1000 operating systems supported including Windows, macOS, BSDs, and 100s of Linux distros. All with automated downloads and configuration.
A GUI to browse and restore restic backup repositories.
A simple, cross-platform restic backup GUI for browsing and restoring restic repositories.
Network recon framework.
IVRE is an open-source framework for network recon. It relies on open-source well-known tools (Nmap, Masscan, ZGrab2, ZDNS and Zeek (Bro)) to gather data (network intelligence), stores it in a database (MongoDB is the recommended backend), and provides tools to analyze it.
Official cross-platform Nmap Security Scanner GUI.
Zenmap is the official Nmap Security Scanner GUI. It is a multi-platform (Linux, Windows, Mac OS X, BSD, etc.) free and open source application which aims to make Nmap easy for beginners to use while providing advanced features for experienced Nmap users. Frequently used scans can be saved as profiles to make them easy to run repeatedly. A command creator allows interactive creation of Nmap command lines. Scan results can be saved and viewed later. Saved scan results can be compared with one another to see how they differ. The results of recent scans are stored in a searchable database.
The Web-scale GUI for MongoDB.
MongoDB client for the web. Query your data directly from your browser. You can host it locally, or anywhere else, for you and your team.